Patient Sources

NCR has three sources from which to attract patients into its studies:

1. The Research Database: Both NCR research centers maintain a database of individuals who have an interest in participating in a research study.

Most individuals in these databases have participated in one or more research studies. They first come to the research center when responding to a research ad, on self referral when the research center is advocated by a friend, or on referral from their primary physician. In this manner, most patients in our database self-selected themselves as being interested in participating in a research study. In contrast, only 1-3% of a people in a practice database historically volunteer to participate in a research study.

A profile of key characteristics of these databases follows. 

Total Patients
6000 Therapeutic Category # of Patients  
Females 60% CHD 1050
Caucasians 55% Diabetes 2400
African American 50% Dyslipidemia 3800
Over 65 years old 25% ED 250
    Fibromyalgia 275
    GERD 1500
    Hot Flashes/vasomotor symptoms 1250
    Hypertensive 1700
    IBS 200
    Insomnia/sleep disorders 1350
    Metabolic Syndrome 2250
    Migraine 400
    Obesity (BMI > 30) 2000
    Osteoarthritis 1500
    Osteoporosis/osteopenia 1100
    Overactive bladder 1200
    Smokers 1200



2. Collaborating Physician Investigators: Collaborating physician investigators maintain an active patient practice and participate with us in conducting research. Many of their patients consent to participate in our research program. Following are general statistics from these collaborating physician offices. 

Internal Medicine Offices   Gastrointerology   OB/GYN  
Total patient population: 18,446   Total patient population: 12,200   Total patient population 98,233  
Hyperlipidemia 21.7% GERD 9.8% Female sexual dysfunction
4.9%
Hypertension 22.1% IBS 12% Osteoporosis/osteopenia
18.4%
Obesity 18.0% Dyspepsia 6.7% Overactive bladder
14.4%
Osteopenia/Osteoporosis 9.7%     Vasomotor symptoms
17.7%



3. Patient Mailing Lists: NCR has mailing lists of people with self-professed common medical problems and periodically mails IRB-approved flyers to these individuals making them aware of the studies currently being recruited at NCR. These mailings typically generate a 1-3% response (phone or mail-in card) and a 0.5 to 1.5% study enrollment rate (e.g. a 10,000 patient mailing can be expected to generate 50-150 patient appointments for a given study).

An indication of the medical problems and number of names on some of our mailing lists are provided below:


Depression Diabetes ED GERD
26,000 41,000 5,000 17,000
       
Hyperlipidemia Hypertension Insomnia Migraine
67,000 65,000 27,000 40,000
       
OAB Osteoarthritis Osteoporosis Psoriasis
25,000 31,000 20,000 24,000